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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: Successful induction of deep hypothermia by isoflurane anesthesia and cooling in a non-hibernator, the rat

Fig. 4

Effects of induction and maintenance of hypothermia on serum levels of organ injury markers. Serum levels of AST, ALT, LDH and BUN are shown in panels ad, respectively. Cont represents the value in rats before inducing hypothermia. 0 h shows the value in rats just after reaching 15 °C. 3 h and 6 h show the values in rats maintained at 15 °C for 3 h and 6 h, respectively. Comparison between black symbols (Cont vs 0 h) revealed that the process of induction of hypothermia does not affect serum levels of organ injury markers. On the other hand, red symbols (3 h and 6 h) indicate that maintenance of the hypothermic condition significantly increased serum levels of these markers. Values are means ± SD (n = 5). The blue horizontal lines denote statistical significance (p < 0.05)

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