Fig. 4

CASC7 overexpression attenuated the miR-34a-5p mimic-mediated inhibition of TP73 expression. a, c TP73 mRNA expression determined by qRT-PCR analysis, and b, d TP73 protein level determined by western blot in human PTC cell lines (K1 and TPC-1) co-transfected with miR-34a-5p mimic/mimic NC and CASC7 overexpression vector/empty vector. *P < 0.05, **P < 0.01 vs. mimic NC + Vector; ^#P < 0.05, ^##P < 0.01 vs. mimic NC + CASC7 or Vector + miR-34a-5p mimic. Data are expressed as the mean ± standard deviation (n = 3)