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Fig. 1 | The Journal of Physiological Sciences

Fig. 1

From: Non-neuronal cardiac acetylcholine system playing indispensable roles in cardiac homeostasis confers resiliency to the heart

Fig. 1

Characterization of the choline acetyltransferase knockdown (ChATKD) transgene in the heart. a Knockdown transgene of ChAT-specific sequences for miRNA synthesis is verified to be restrictively expressed in the heart by the GFP protein expression. GFP expression levels in ChATKD mice hearts are comparable to those in ChAT tg mice hearts. b ChAT mRNA expression is lower in the ChATKD heart than in control mice (P = 0.001). c Cardiac protein expression levels of ChAT are lower in the ChATKD heart than in the control heart. d An ACh content is lower in the ChATKD heart than in the control heart (P = 0.001)

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