| | slc26a3(+/+ or +/−) | slc26a3(−/−) | p values |
|---|
Cecum | | | |
Isc | 0.28 ± 0.13 | 1.45 ± 0.29 | 0.007* |
Gt | 17.2 ± 2.2 | 13.1 ± 0.9 | 0.096 |
Proximal colon | | | |
Isc | 1.21 ± 0.25 | 1.92 ± 0.20 | 0.059 |
Gt | 19.7 ± 2.6 | 17.9 ± 2.4 | 0.633 |
Middle-distal colon | | | |
Isc | 0.64 ± 0.22 | 1.37 ± 0.10 | 0.010* |
Gt | 13.7 ± 1.5 | 12.3 ± 0.7 | 0.396 |
- These values were determined in the experiments shown in Figs. 2 and 3. The Isc, with a positive sign representing net positive charge flowing from mucosa to serosa, is presented as µEq cm−2 h−1, and Gt as mS cm−2. Statistical comparisons were performed by unpaired t test
- *0.01 < p < 0.05 between slc26a3(+/+ or +/−) and slc26a3(−/−). n = 5 for slc26a3(+/+ or +/−) and 5–6 for slc26a3(−/−). [Additional information; numbers slc26a3(+/−)] vs. slc26(+/+)] in the control group are 1 (vs. 4) in the cecum, 0 (vs. 5) in the proximal colon and 1 (vs. 4) in the middle-distal colon. Isc and Gt from slc26a3(+/−) were 0.16 and 12.0 in the cecum, and 0.46 and 10.5 in the middle-distal colon (in µEq cm−2 h−1, and mS cm−2).]
