Skip to main content
Fig. 8 | The Journal of Physiological Sciences

Fig. 8

From: Moesin is involved in microglial activation accompanying morphological changes and reorganization of the actin cytoskeleton

Fig. 8

NO and TNF-α secretion by primary microglia is upregulated by treatment with LPS. a The cell lysates of WT and Msn-KO microglia treated with or without LPS were blotted with an anti-iNOS antibody. Expression of iNOS was upregulated by the treatment with LPS in the WT and Msn-KO microglia. b NO release from the WT and Msn-KO microglia treated with or without LPS was measured by Griess assay, and shown by closed and open columns, respectively. NO release was upregulated by the treatment with LPS in the WT and Msn-KO microglia. c TNF-α release from the WT and Msn-KO microglia treated with or without LPS was measured by ELISA, and shown by closed and open columns, respectively. TNF-α release was upregulated by the treatment with LPS in the WT and Msn-KO microglia. Results are expressed as mean value ± SEM. WT (N = 7), Msn-KO (N = 4). *p < 0.05 vs. control

Back to article page