Fig. 5

NK cells boosted PA-infected macrophage to M1 polarization through secreting exosomes. NK cell-derived exosomes or PBS were incubated with macrophage following PA infection. Then, a the percentage of M1- and M2-polarized macrophage were measured by flow cytometry. b The results of flow cytometry were analyzed and shown. c and d qRT-PCR was implemented to detect the expression of iNOS and Arg-1 in macrophages, as well as the expression of TNF-α, IL-1β and IL-10. **P < 0.01 compared with Control group, and ^##P < 0.01 contrasted with PA group