Fig. 3

PA-infected macrophage to M2 polarization was facilitated following the ability of NK cells to secret exosomes was inhibited. The blocker of exosomes generation, GW4869, was used to stimulate NK cells, and then the cells were co-cultured with macrophage. a and b Flow cytometry was executed to examine the percentage of M1- and M2-polarized macrophage. c The relative expression of iNOS and Arg-1 in macrophages was measured by qRT-PCR. d The expression of TNF-α, IL-1β and IL-10 in macrophages was detected by qRT-PCR. **P < 0.01 compared with Control group