Fig. 1

NK cells elimination promoted M2 macrophage polarization in the mouse model of PA lung infection. a The bacterial burden in the right lung tissues of mice was analyzed using CFU counting. **P < 0.01 compared with Control group. b Flow cytometry was carried out to analyze the number of NK cells in lung tissues of mice. NK(-): NK cell-depleted mice, ^##P < 0.01 compared with PA + isotype group. c, d The cell numbers of M1-polarized and M2-polarized macrophages in lung tissues were ensured using flow cytometry, and then counted. **P < 0.01 compared with Control group, both ^#P < 0.05 and ^##P < 0.01 contrasted with PA group. e The expression of iNOS and Arg-1 in lung tissues was measured by qRT-PCR. **P < 0.01 compared with Control group, ^##P < 0.01 contrasted with PA group