Fig. 5

Modulation of pain-related high-gamma oscillation sources by selective attention and heterotopic noxious counter-stimulation (HNCS). Source estimation of high-gamma oscillations (at 86 Hz, 158 ms post-stimulation) represented as t values, based on a voxelwise two-tailed paired t test on time–frequency source space (a patients with IBS; b control group). Time courses of high-gamma oscillations during HNCS and HICS blocks were compared to those during baseline block. Positive and negative relationships are depicted by warm and cool colors, respectively. Whole-brain t-maps were thresholded at p < 0.05, false discovery rate corrected for the whole brain. Statistical results and MNI coordinates of strongest relationships (peak locations) are provided in the “Results” section. Hz: hertz; ms: milliseconds; SI: primary somatosensory cortex; ACC: anterior cingulate cortex; DLPFC: dorsolateral prefrontal cortex; IBS: irritable bowel syndrome; HICS: heterotopic innocuous counter-stimulation; HNCS: heterotopic noxious counter-stimulation