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Table 1 Expression of GLUT1, GLUT3, and KATP channel subunits in HUVECs under normoxia and hypoxia

From: Hypoxia induces the translocation of glucose transporter 1 to the plasma membrane in vascular endothelial cells

Gene name

Normoxia

Hypoxia

P Value

Mean ± SEM

Mean ± SEM

GLUT1

0.483 ± 0.041

1.729 ± 0.149

< 0.01

GLUT3

0.708 ± 0.172

1.544 ± 0.148

< 0.05

Kir6.1

0.868 ± 0.080

1.044 ± 0.126

n.s.

Kir6.2

1.223 ± 0.823

0.844 ± 0.229

n.s.

SUR-1

0.997 ± 0.317

1.083 ± 0.122

n.s.

SUR-2A

1.117 ± 0.216

1.035 ± 0.130

n.s.

SUR-2B

0.899 ± 0.110

0.972 ± 0.039

n.s.

  1. The mRNA levels of GLUTs and KATP channel subunits were analyzed by real-time PCR [11, 13]. Data are shown as relative values normalized with 18S RNA. Data are expressed as the mean ± SEM of 4 independent experiments. P-values were analyzed by an unpaired t-test. n.s. not significant
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The Journal of Physiological Sciences

ISSN: 1880-6562

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