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Fig. 6 | The Journal of Physiological Sciences

Fig. 6

From: Mitogen-activated protein kinase p38 modulates pacemaker ion channels differentiation in P19-derived pluripotent cells

Fig. 6

Effects of p38 MAPK inhibition on Csx/Nkx2.5 and GATA4 proteins expression. A p38 MAPK inhibitor SB203580 reduced expression of Csx/Nkx2.5 (a), GATA4 (b) and phospho-GATA4 proteins (c) in a concentration-dependent manner assessed by Western blot analysis in P19-derived cardiomyocytes. d The ratio of phospho-GATA4 proteins to total GATA4 proteins with or without SB203580 (1–10 μM) assessed by data in panels (b, c). *p < 0.01 vs. SB (−) at day 10

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