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Fig. 7 | The Journal of Physiological Sciences

Fig. 7

From: Impact of delayed ventricular wall area ratio on pathophysiology of mechanical dyssynchrony: implication from single-ventricle physiology and 0D modeling

Fig. 7

Clinical impact of an uncoordinated wall motion at earlier activated ventricular wall. a A representative speckle tracking echocardiogram at three segments applied to earlier activated ventricular wall among seven segments of global longitudinal tracking in a patient with single ventricle. The region of interest did not consider the insertion point of the rudimentary septum (red triangle). Using an obtained strain curve (white dotted line), an uncoordinated wall motion was evaluated by calculating the strain ratio (Rstrains) of two values during the QRS period and the ejection period as an equation at the bottom. b Positive correlation between Rstrains and plasma B-type natriuretic peptide (BNP) level in 62 investigated patients with single ventricle. c Negative correlation between Rstrains and estimated ventricular elastance at end-systole (estEes). Green curves indicate a 95% confidence ellipse; ρ, Spearman’s rank correlation coefficient

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