Fig. 10

Effect of tolfenamic acid on OA-treated PC12 cells. PC12 cells were treated with tolfenamic acid (5 and 10 μM) for 24 h, then with OA for 6 h. Tolfenamic acid treatment significantly prevent OA-induced cell death (a). Tolfenamic acid treatment significantly decreased the expression of p-tau Ser396 (b), Thr231 (c), and p-PP2A Tyr307 (d). All results are expressed as the means ± SEM. n = 3; ^##p < 0.01 versus control; *p < 0.05, **p < 0.01 versus OA