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Fig. 6 | The Journal of Physiological Sciences

Fig. 6

From: Cardiac specific transcription factor Csx/Nkx2.5 regulates transient-outward K+ channel expression in pluripotent P19 cell-derived cardiomyocytes

Fig. 6

ATP-sensitive K+ currents (IK,ATP) in P19CL6-derived cardiomyocytes and P19CL6-Csx-derived cardiomyocytes. Sample current recordings at a holding potential of ‒ 40 mV (a, b). Instantaneous current–voltage relationships (c, d) were obtained by ramp pulses from + 60 mV to ‒ 120 mV at the rate of ‒ 0.18 V/s, before (i) and after (ii) application of 100 µmol L−1 cromakalim. Group data (n = 4) for the cromakalim-sensitive current, IK,ATP (ii)–(i) are plotted in the early stage (dotted line) and in the late stage (solid line)

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