Fig. 5

Attenuated contraction of MASM isolated from DKO mice. Fluo-8-loaded MASM were stimulated with 0.3 µM ionomycin. A difference in the planar cell surface area before and after the addition of ionomycin (∆A/A₀) was determined in each cell and compared in C2α^flox/flox (n = 11) and C2α^flox/flox; SM22α-Cre mice (n = 12) (a), in wild-type (C2β^+/+) (n = 14) and C2β^−/− (n = 14) mice (b), and in C2α^flox/flox C2β^−/− (n = 13) and C2α^flox/flox C2β^−/−; SM22α-Cre (n = 14) mice (c). Representative images of cells (left) and quantified data (right) are shown. ^★★p < 0.01