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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice

Fig. 2

Expression of the smooth muscle-specific proteins in the aorta and mesenteric artery of control and knockout mice. a Immunofluorescence staining of the smooth muscle-specific proteins Mhc11 and SM22α in the aorta of control (C2αflox/flox; C2β−/−) and DKO (C2αflox/flox; C2β−/−; SM22α-Cre) mice. The SM layer was similarly stained by anti-Mhc11 and anti-SM22α antibodies. b Immunofluorescent staining of Mhc11 in the mesenteric artery of wild-type (BL6) (left), C2αflox/flox C2β−/− (middle), and C2αflox/flox C2β−/−; SM22α-Cre mice (right). White arrowheads indicate similar expression of Mhc11 in the SM. In a and b, nuclei were stained with DAPI

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