Understanding vestibular-related physiological functions could provide clues on adapting to a new gravitational environment

Table 1 Summary of change in the gene expression of the hypothalamic feeding- regulating neuropeptides after exposure to 2g hypergravity compared with sham-1g

mRNA	After 3 days exposure to hypergravity		After 2 weeks exposure to hypergravity		After 8 weeks exposure to hypergravity
mRNA	sham-2g	VL-2g	sham-2g	VL-2g	sham-2g	VL-2g
CRH	↑	→	↑	→	→	→
POMC	↓	↓	↑	→	→	→
CART	↓	↓	→	→	→	→
NPY	↑	↑	→	→	→	→
AgRP	↑	↑	→	→	→	→
MCH	→	→	→	→	→	→
orexin	↑	↑	→	→	→	→

ISSN: 1880-6562