Fig. 6

The localization of the ectopic foci in the BALB/c PV myocardium. The application of the norepinephrine (NE) in PV mouth region in all cases (a); similarly phenylephrine-induced (PHE) ectopic automaticity was also initiated in PV mouth in all experiments (b); in case of isoproterenole (ISO) ectopic foci were localized in the same region (c) in all experiments except one. A postganglionic nerves stimulation (PNS) induced ectopic automaticity in PV tissue preparation only in two experiments (d). A dotted ring restricts PV mouth region. The position of the marks in the a–c panels is determined on the isochronic maps analysis as a central point of the depolarized area after the first ms of the excitation