Fig. 5

Change in exercise efficiency caused by bilateral administration of a dopamine receptor antagonist to the septum. a Oxygen uptake (VO₂) during obstacle treadmill running after training with or without injection of dopamine receptor antagonists into bilateral septum (n = 8). The left panel shows VO₂ during obstacle treadmill running after training, while the right panel shows VO₂ during normal treadmill running after training. Representative image of c-Fos expressions in the b septum and d hippocampus-CA3. Scale bars = 50 μm. The c-Fos expression values in the c septum (n = 5) and e hippocampus-CA3 (n = 5). Data are presented as mean ± standard error. One-way analysis of variance, followed by the Bonferroni test, was used