Fig. 1
Exercise efficiency before and after training of treadmill running with intermittent obstacles. a Model of treadmill running with intermittent obstacles. The belt-type treadmill chamber (width, 50 mm; length, 295 mm; height, 60 mm) was sealed in a rectangular parallelepiped glass case, and there were air holes in the front and rear. The rear air hole was connected to a tube used for measuring oxygen uptake (VO2). b Average VO2 during treadmill running with or without obstacles before and after training (n = 11). Training was performed with obstacle treadmill running. c Alteration of VO2 during treadmill running with obstacles in each mouse before and after training of treadmill running with obstacles (n = 11). d Average VO2 during treadmill running with or without obstacles before and after training (n = 11). Training was performed without obstacle treadmill running. e VO2 at rest before and after training (n = 11). Data are presented as mean ± standard error. Paired t test was used. Asterisk indicates p < 0.05 vs. VO2 during no obstacle treadmill running before training