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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: Augmented fear bradycardia in rats with heart failure

Fig. 4

a Thirty-second averaged time courses of MAP and HR while conscious, free-moving CHF (n = 8) rats, of which microinjection sites were located within the l/vlPAG, were exposed to 5-min of WNS at 90 dB at 5–15 or 30–40 min after bilateral microinjection into the l/vlPAG of saline (100 nl) or Tiron (200 mM diluted in 100 nl saline). Values represent mean ± SEM *P < 0.05, vs. baseline, detected by the Dunnett’s post hoc test following one-way repeated-measures ANOVA. b Comparisons of 5 min averaged changes from baseline in MAP and HR during WNS exposure between saline and Tiron microinjections into the l/vlPAG and between 5–15 and 30–40 min after microinjection in the CHF rats. NS no significant differences between saline and Tiron microinjections and between 5–15 and 30–40 min after administration, examined by two-way repeated-measures ANOVA followed by the Tukey’s post hoc tests

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