Fig. 3
From: Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia
The current–voltage (I–V) relationships of WT and HCN2-Tg mouse myocytes in 3 mM K+ solution. a The current traces of WT myocytes recorded in the control condition. b The current traces of WT myocytes in the presence of 1 mM barium (Ba2+). The inset shows the pulse protocol. c The I–V relationships of the background current of WT mouse myocytes. The amplitudes of the background current were measured at the end of the hyperpolarizing pulses: filled circle, control; open circle, in the presence of 1 mM Ba2+. d The current traces of HCN2-Tg myocytes in the cotrol condition. e The current traces of HCN2-Tg myocytes in the presence of 1 mM Ba2+. f The I-V relationships measured in HCN2-Tg myocytes (same conditions as in c)