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Table 1 Characteristic differences in wild-type and mdx mice

From: Renal involvement in the pathogenesis of mineral and bone disorder in dystrophin-deficient mdx mouse

 

Wild-type

mdx

P value

Body weight (g)

29.16 ± 1.39

29.30 ± 1.97

0.86

Kidney weight (mg)

190 ± 20

210 ± 30

0.19

Relative kidney volume (%)

0.67 ± 0.03

0.71 ± 0.07

0.09

Ca (mg/dl)

10.82 ± 0.49

12.23 ± 0.33

0.0001

IP (mg/dl)

12.11 ± 0.66

12.68 ± 0.87

0.12

TP (mg/dl)

4.98 ± 0.20

5.51 ± 0.22

0.0001

ALB (mg/dl)

3.10 ± 0.08

3.41 ± 0.17

0.0001

BUN (mg/dl)

26.83 ± 3.01

30.10 ± 3.29

0.03

UA (mg/dl)

4.94 ± 0.63

5.39 ± 0.53

0.12

CRE (mg/dl)

0.126 ± 0.020

0.132 ± 0.020

0.51

U-CRE (mg/dl)

14.04 ± 5.83

14.64 ± 2.88

0.78

Ccr

113.28 ± 49.27

112.79 ± 25.03

0.98

Urine volume (ml/day)

1.2 ± 0.8

2.3 ± 0.3

0.04

Hematocrit (%)

45.2 ± 2.1

48.9 ± 1.1

0.01

Activity levels (times/day)

10357.9 ± 1051.2

8657.4 ± 2093.7

0.03

  1. Values are the mean ± SD (n = 10, each group except urinary volume: n = 4–5, hematocrit: n = 5, and activity levels: n = 8–12, each group)
  2. Ca calcium, IP inorganic phosphate, TP total protein, ALB albumin, BUN blood urea nitrogen, UA uremic acid, CRE creatinine, U-CRE urine creatinine, Ccr creatinine clearance