|
Time after treatments (h)
|
3
|
12
|
20
|
|---|
|
Plasma concentration of K+ (mEq/l)
|
|
Sham operation
|
8.1 ± 0.4
|
6.9 ± 0.3
|
7.0 ± 0.3
|
|
Bilateral nephrectomy
|
8.6 ± 0.3
|
8.5 ± 0.4**
|
10.2 ± 0.6**
|
|
Plasma concentration of BUN (mg/dl)
|
|
Sham operation
|
34.6 ± 5.8
|
20.3 ± 1.5
|
17.7 ± 0.7
|
|
Bilateral nephrectomy
|
48.8 ± 2.0
|
94.9 ± 2.4**
|
123.8 ± 2.9**
|
|
Plasma concentration of Cre (mg/dl)
|
|
Sham operation
|
0.23 ± 0.02
|
0.22 ± 0.01
|
0.23 ± 0.02
|
|
Bilateral nephrectomy
|
0.66 ± 0.03**
|
1.58 ± 0.16**
|
2.7 ± 0.02**
|
- Data are presented as the mean ± SEM (each group at each time point, n = 6)
- *P < 0.05, **P < 0.01 compared with the saline-treated group. Plasma K+, BUN, and Cre in untreated rats (n = 6) were 8.6 ± 0.1 mEq/L, 17.4 ± 0.5 mg/dl, and 0.25 ± 0.01 mg/dl respectively
