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Table 2 Effects of i.p. bilateral nephrectomy (Nx) or sham operation on plasma concentrations of potassium (K+), blood urea nitrogen (BUN), and creatinine (Cre) at 3, 12, and 20 h after treatment

From: Effects of acute kidney dysfunction on hypothalamic arginine vasopressin synthesis in transgenic rats

Time after treatments (h)

3

12

20

Plasma concentration of K+ (mEq/l)

Sham operation

8.1 ± 0.4

6.9 ± 0.3

7.0 ± 0.3

Bilateral nephrectomy

8.6 ± 0.3

8.5 ± 0.4**

10.2 ± 0.6**

Plasma concentration of BUN (mg/dl)

Sham operation

34.6 ± 5.8

20.3 ± 1.5

17.7 ± 0.7

Bilateral nephrectomy

48.8 ± 2.0

94.9 ± 2.4**

123.8 ± 2.9**

Plasma concentration of Cre (mg/dl)

Sham operation

0.23 ± 0.02

0.22 ± 0.01

0.23 ± 0.02

Bilateral nephrectomy

0.66 ± 0.03**

1.58 ± 0.16**

2.7 ± 0.02**

  1. Data are presented as the mean ± SEM (each group at each time point, n = 6)
  2. *P < 0.05, **P < 0.01 compared with the saline-treated group. Plasma K+, BUN, and Cre in untreated rats (n = 6) were 8.6 ± 0.1 mEq/L, 17.4 ± 0.5 mg/dl, and 0.25 ± 0.01 mg/dl respectively