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Fig. 6 | The Journal of Physiological Sciences

Fig. 6

From: Suramin protects hepatocytes from LPS-induced apoptosis by regulating mitochondrial stress and inactivating the JNK-Mst1 signaling pathway

Fig. 6

The JNK pathway is involved in LPS-mediated hepatocyte death and mitochondrial stress. a, b Mitochondrial ROS production was determined using flow cytometry. c–e ELISAs were used to confirm the concentrations of GSH, SOD and GPX in response to JNK activator. f Caspase-9 activity was determined using an ELISA. g Hepatocyte viability was observed using the LDH release assay in cells treated with the JNK activator. h, i The TUNEL assay was used to observe the number of apoptotic cells. *p < 0.05

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