Fig. 6From: Suramin protects hepatocytes from LPS-induced apoptosis by regulating mitochondrial stress and inactivating the JNK-Mst1 signaling pathwayThe JNK pathway is involved in LPS-mediated hepatocyte death and mitochondrial stress. a, b Mitochondrial ROS production was determined using flow cytometry. c–e ELISAs were used to confirm the concentrations of GSH, SOD and GPX in response to JNK activator. f Caspase-9 activity was determined using an ELISA. g Hepatocyte viability was observed using the LDH release assay in cells treated with the JNK activator. h, i The TUNEL assay was used to observe the number of apoptotic cells. *p < 0.05Back to article page