Fig. 3

Suramin modulates the mitochondrial dynamics balance. a–i Western blotting was used to observe alterations in the levels of mitochondrial dynamics-related factors. Levels of mitochondrial fission factors, such as Drp1, Mff, and Fis1, were measured. Levels of mitochondrial fusion proteins, such as Mfn2, Mfn1 and OPA1, were also determined. Levels of mitophagy markers, such as Parkin and Beclin1, were also detected following the LPS treatment. j, k Immunofluorescence staining for mitochondrial dynamics using the mitochondrial antibody Tom-20. Mitochondrial length was determined to reflect the mitochondrial dynamics. Ad-Mst1 Mst1 adenovirus, Ad-ctrl control adenovirus, *p < 0.05