Fig. 7
Cross sections of dorsal root ganglion neurons (DRG) from control (a), rats received a high dose of pyridoxine (b), rats treated with CE (c), and the chart of DRG cells number (d). There are two types of cells in DRG neurons: A type or B type. Type A cells have a large size and less intensely central nucleolus (arrow in a). B cells are characterized by a nucleus containing basophilic and many smaller chromatin condensations (arrow in b). The result of the cell count showed that the number of A-cells are more abundant than B-cells in the control group. However, in the neuropathic group compared to the control, the number of B-cells increased significantly (*p < 0.001). CE treatment abolished the effect of pyridoxine toxicity and led to an increase in the number of A-cells (#p < 0.001) (H&E magnification 200×, scale bar 50 µm)