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Fig. 6 | The Journal of Physiological Sciences

Fig. 6

From: Improvement of pyridoxine-induced peripheral neuropathy by Cichorium intybus hydroalcoholic extract through GABAergic system

Fig. 6

Pyridoxine-induced neuropathy and investigation of the role and probable mechanism of CE in hot plate test. a Reaction time to heat increased in pyridoxine group compared with the control (ctrl) group. *p < 0.001. b The rats receiving CE decreased reaction time in comparison with saline (NS) group (*p < 0.05). Picrotoxin (picro) treatment group increased the duration of response to heat but Mk-801 had no significant effect (#p < 0.001). Data are shown as the mean ± SEM (N = 7 per group)

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