Fig. 6From: Improvement of pyridoxine-induced peripheral neuropathy by Cichorium intybus hydroalcoholic extract through GABAergic systemPyridoxine-induced neuropathy and investigation of the role and probable mechanism of CE in hot plate test. a Reaction time to heat increased in pyridoxine group compared with the control (ctrl) group. *p < 0.001. b The rats receiving CE decreased reaction time in comparison with saline (NS) group (*p < 0.05). Picrotoxin (picro) treatment group increased the duration of response to heat but Mk-801 had no significant effect (#p < 0.001). Data are shown as the mean ± SEM (N = 7 per group)Back to article page