Fig. 1

Effect of omeprazole on Mg²⁺ transport across Caco-2 monolayers. The rate of Mg²⁺ transport across control (a), 200-ng/ml omeprazole-treated (b), and 400-ng/ml omeprazole-treated Caco-2 monolayers (c). White bar; total Mg²⁺ transport, gray bar; Mg²⁺ channel-independent Mg²⁺ transport, black bar; Mg²⁺ channel-dependent Mg²⁺ transport. *P < 0.05, **P < 0.01, ***P < 0.001 compared with its corresponding CCh-untreated group. (n = 6). The rate of total (d), Mg²⁺-channel independent (e), and Mg²⁺-channel dependent (f) Mg²⁺ transport of control and omeprazole-treated Caco-2 monolayers. *P < 0.05, **P < 0.01, ***P < 0.001 compared with its corresponding control group (n = 6)