Fig. 4
From: MARCKS phosphorylation and amylase release in GLP-1-stimulated acini isolated from rat pancreas
Inhibition of GLP-1-induced amylase release by MARCKS-related peptide (MANS). After pretreatment with RNS (50 μM) or MANS (50 μM) for 15 min, acini were incubated with or without GLP-1 (25 nM) for 15 min. Amylase release was expressed as the percentage of the total amylase activity. Values show the means ± SE from three independent experiments. The asterisk indicates a significant difference (P < 0.05) compared with the control in absence of GLP-1