Fig. 6
From: The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans
Working model for the role of ARF-1.2 in the polarized membrane traffic in the excretory canals. a Schematic structure of the excretory cell. Varicosities, which are frequently observed during L1 larval stages and under hyperosmotic conditions, contain ER-Golgi networks and are considered to be growth sites of the canals. b Model of polarized membrane traffic in the excretory canals. Solid lines show established trafficking pathway in the previous study [16] and broken lines indicate hypothetical mechanisms based on the present study. RE recycling endosome, AEE apical early endosome, BEE basal early endosome, LE late endosome