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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: Testosterone-mediated upregulation of delayed rectifier potassium channel in cardiomyocytes causes abbreviation of QT intervals in rats

Fig. 2

Reduction of Kv7.1 by castration and its upregulation by testosterone. Changes in K channel and K channel-related genes were assessed by qRT-PCR in ventricular cardiomyocytes from castrated male rats: IKs (Kv7.1, minK), IKr (Kv11.1, MiRP1), Ito (Kv4.2, Kv4.3, KChIP2) and IK1 (Kir2.1). Testosterone was intraperitoneally administered (1000 µg/kg) once a day for 2 weeks from day 7 after castration. Data are presented as the mean value ± SEM (n = 6). *< 0.05 vs castration

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