Fig. 1

Treadmill exercise ameliorates motor function deficits in MPTP mice. a Pre-rota-rod test; a significant difference between C57BL mice and MPTP mice on mean latency to fall before the intervention of the treadmill exercise, t-test was used to compare whether C57BL mice and MPTP mice have different average values. b Post-rota-rod test; MPTP mice with treadmill exercise performed better on the rota-rod compared with the non-exercised MPTP mice. LSD post hoc test after ANOVA. Values are presented as mean ± SEM from ten mice per group. Saline control (CON), MPTP treatment with probenecid (MPTP), and MPTP treatment with probenecid plus treadmill exercise (MPTP-TE)