Fig. 1
Current scheme for the regulation of smooth muscle contraction. GPCR G-protein coupled receptor; PLCβ phospholipase Cβ; PIP 2 phosphatidylinositol 4,5-bisphosphate; IP 3 inositol 1,4,5-tripsphosphate; DAG diacylglycerol; PKC protein phosphatase C; SR sarcoplasmic reticulum; CaM calmodulin; MLCK myosin light chain kinase; MLCP myosin light chain phosphatase; GEF guanine nucleotide exchange factor; ROCK RhoA/rho-associated coiled-coil-containing protein kinase; CPI-17 PKC-potentiated inhibitory protein of 17 kDa. See the text for details