Fig. 4

The number of Fos-like immunoreactivity (LI) cells in the supraoptic (SON) nucleus (A-a), the paraventricular nucleus (PVN) (B-a), the area postrema (AP) (C-a), the medial nucleus of the solitary tract (mNTS) (C-b) and the caudal NTS (cNTS) (C-c) after administration of cisplatin with pretreatment of oxytocin receptor antagonist (OXTR-A) pretreatment in rats. The number of Fos- expressingon in OXT-LI cells in the SON (A-b) and the PVN (B-b). Values represent the mean ± SEM (each group, n = 6–7). *p < 0.05 and **p < 0.01 compared with the vehicle/vehicle group. ^# p < 0.05 and ^## p < 0.01 compared with the OXTR-A/vehicle group. ^$ p < 0.05 and ^$$ p < 0.01 compared with the OXTR-A/cisplatin group