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Table 3 Distribution and properties of β-AR subtypes

From: β-Adrenergic signaling, monoamine oxidase A and antioxidant defence in the myocardium of SHR and SHR-mtBN conplastic rat strains: the effect of chronic hypoxia

  SHR SHR/H SHR-mtBN SHR-mtBN/H
β2 (%) 24.03 ± 0.30 31.12 ± 1.42+ 32.97 ± 2.01* 31.15 ± 0.42
K iβ2 (nM) 0.80 ± 0.53 1.43 ± 0.17 4.80 ± 1.25 0.75 ± 0.21
K iβ1 (µM) 0.73 ± 0.06 0.77 ± 0.25 0.70 ± 0.07 0.31 ± 0.03
  1. Data are means (±SEM) of three separate experiments performed in triplicates
  2. β 2 (%) percentage of β2-ARs of total myocardial β-ARs, K i β 2 (β 1 ) apparent dissociation constant representing the affinity of ICI 118.551 to β2-ARs (β1-ARs)
  3. p < 0.05 SHR vs. SHR-mtBN; + p < 0.05 SHR vs. SHR/H