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Table 3 Distribution and properties of β-AR subtypes

From: β-Adrenergic signaling, monoamine oxidase A and antioxidant defence in the myocardium of SHR and SHR-mtBN conplastic rat strains: the effect of chronic hypoxia

 

SHR

SHR/H

SHR-mtBN

SHR-mtBN/H

β2 (%)

24.03 ± 0.30

31.12 ± 1.42+

32.97 ± 2.01*

31.15 ± 0.42

K iβ2 (nM)

0.80 ± 0.53

1.43 ± 0.17

4.80 ± 1.25

0.75 ± 0.21

K iβ1 (µM)

0.73 ± 0.06

0.77 ± 0.25

0.70 ± 0.07

0.31 ± 0.03

  1. Data are means (±SEM) of three separate experiments performed in triplicates
  2. β 2 (%) percentage of β2-ARs of total myocardial β-ARs, K i β 2 (β 1 ) apparent dissociation constant representing the affinity of ICI 118.551 to β2-ARs (β1-ARs)
  3. * p < 0.05 SHR vs. SHR-mtBN; + p < 0.05 SHR vs. SHR/H
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The Journal of Physiological Sciences

ISSN: 1880-6562

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