Fig. 2

Quantitative analysis of the effect of somatostatin applied to the lumbo-sacral spinal cord. a Representative recording traces of intraluminal pressure change before and after intrathecal administration of somatostatin at a dose of 0.6 (upper) or 6 nmol (lower). Bar graphs summarize b expelled liquid volume (ml/20 min) and c frequency of contractions (contractions/20 min) before saline injection, after saline injection and after somatostatin (0.6 or 6 nmol) injection. Each value represents the mean ± SD (n = 5). *Significantly different between two groups (P < 0.05). d Time-dependent changes in frequency of contractions before and after injection of 6 nmol somatostatin (n = 5) are shown