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Fig. 3 | The Journal of Physiological Sciences

Fig. 3

From: Inhibition of ghrelin-induced feeding in rats by pretreatment with a novel dual orexin receptor antagonist

Fig. 3

Numbers of Fos-immunoreactive (IR) neurons in the paraventricular nucleus (PVN), the arcuate nucleus (Arc) and the lateral hypothalamic area (LHA) at 90 min after intracerebroventricular (icv) administration of ghrelin (2 nmol) or saline, pretreated with orexin receptor antagonist (DORA, ACT462206) or saline. Data for the number of Fos-IR neurons are expressed as the mean ± SEM (n = 4–7). *P < 0.05 and **P < 0.01, compared with saline + saline-injected rats. # P < 0.05 and ## P < 0.01, compared with DORA + saline-injected rats. $$ P < 0.01, compared with DORA + ghrelin-injected rats

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