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Fig. 1 | The Journal of Physiological Sciences

Fig. 1

From: Inhibition of ghrelin-induced feeding in rats by pretreatment with a novel dual orexin receptor antagonist

Fig. 1

Effects of intracerebroventricular (icv) administration of ghrelin (1 nmol) or saline pretreatment with an orexin receptor antagonist (DORA, ACT462206; 15 nmol) or saline on cumulative food intake in conscious rats (A). Effects of icv administration of ghrelin (1 nmol) or saline pretreatment with DORA (15 nmol) or saline on cumulative water intake in conscious rats (B). Data for cumulative food intake and water intake are expressed as the mean ± SEM (n = 4–7). *P < 0.05 and **P < 0.01, compared with saline + saline-injected rats. # P < 0.05 and ## P < 0.01, compared with DORA + saline-injected rats. † P < 0.05, compared with saline + ghrelin-injected rats

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The Journal of Physiological Sciences

ISSN: 1880-6562

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