Fig. 6

Mn²⁺ did not permeate the EPA-triggered Ca²⁺ influx pathway. bEND.3 cells were bathed in Ca²⁺-containing solution and were treated with 30 μM EPA (a) or DMSO (c) followed by 1 mM Mn²⁺. Fura 2 ratios are shown in (a) and (c), while the corresponding fluorescence intensities (arbitrary units) at 340 and 380 nm excitations are shown in (b) and (d). Results are mean ± SEM of 29–43 cells from 4 separate experiments