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Table 1 Capacity for acetylcholine release and synapse formation with muscle cells in neuroblastoma tumor cells with or without ATP6V0C expression

From: Neurotransmitter release: vacuolar ATPase V0 sector c-subunits in possible gene or cell therapies for Parkinson’s, Alzheimer’s, and psychiatric diseases

Cell line ACh synthesis ACh secretion Synapse formation ATP6V0C expression
NG108-15 ++ ++ ++ ++
NBr-10A +++ +++ +++ +++
N18 0 0 0 0
N18 + ACh* ++ 0 0 0
N18 + ACh* + V0C ++ ++ + ++
  1. ACh*, cells were soaked in solution containing ACh or transfected with ChAT
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