Neurotransmitter release: vacuolar ATPase V0 sector c-subunits in possible gene or cell therapies for Parkinson’s, Alzheimer’s, and psychiatric diseases

Table 1 Capacity for acetylcholine release and synapse formation with muscle cells in neuroblastoma tumor cells with or without ATP6V0C expression

Cell line	ACh synthesis	ACh secretion	Synapse formation	ATP6V0C expression
NG108-15	++	++	++	++
NBr-10A	+++	+++	+++	+++
N18	0	0	0	0
N18 + ACh*	++	0	0	0
N18 + ACh* + V0C	++	++	+	++

ISSN: 1880-6562