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Fig. 5 | The Journal of Physiological Sciences

Fig. 5

From: Nicotine inhibits activation of microglial proton currents via interactions with α7 acetylcholine receptors

Fig. 5

Nicotine does not affect LPS-increased expression of H+ channels in microglia. (Upper panel) Western blotting of H+ channel, HVCN1, and β-actin in cultured microglia. Microglial cells were treated with 1 μg/ml LPS for 24 h, and nicotine (1 μM) was pre-treated for 1 h before application of LPS. HVCN1 protein is detected at around 32 kDa in whole-cell lysate from microglia. (Lower panel) Relative expression levels of HVCN1 compared to β-actin are shown in control, LPS, and Nic + LPS. *p < 0.05 compared to control

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The Journal of Physiological Sciences

ISSN: 1880-6562

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