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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: Downregulation of the spinal NMDA receptor NR2B subunit during electro-acupuncture relief of chronic visceral hyperalgesia

Fig. 4

AWR scores in response to graded CRD in control vs. model groups, measured on days 1, 3, 5, 7 and 9 (n = 8 rats in each group). a–d Sets of AWR scores in control and model groups in response to CRD stimuli at strengths of 20, 40, 60 and 80 mmHg, respectively. Abscissa Time course of AWR scoring every other day from day 1 to day 9, ordinate AWR scores. Data are presented as mean ± standard error (SE). *Significant difference at P < 0.05 vs. control. Model Rats which developed inflammatory bowel syndrome (IBS) experimentally induced by CRD as described in section "Production of chronic visceral hyperalgesia model", Control rats Intact normal rats which were not subjected to insertion of a balloon and distention, but received gentle touching on the perineal area daily with a sterile cotton swab

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