Fig. 3From: Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disordersStriatal cholinergic interneurons suppress behavioral flexibility via the M4 muscarinic receptor. Activation of striatal cholinergic interneurons increases acetylcholine (ACh) release and stimulates M4 muscarinic receptor, resulting in the suppression of behavioral switching in response to changed contingencyBack to article page