Fig. 3

Schematic membrane potential responses of rat neonatal CA3 neurones to GABA and glycine bath application of GABA and glycine lead to quite identical responses on neonatal CA3 neurone in the presence of TTX, except that GABA and glycine were specifically antagonized by bicuculline and strychnine, respectively, and glycine response disappeared in the 3rd neonatal week. Responses changed polarity from depolarization to hyperpolarization between the 1st and the 2nd postnatal weeks, despite the resting membrane potential remaining unchanged at approximately −65 mV