Electrophysiology, immunophenotype, and gene expression characterization of senescent and cryopreserved human amniotic fluid stem cells

Table 2 Main types of ion currents identified in senescent and cryopreserved AFSC, numbers and percentages of cells where they were found, and mean current densities

Current	I _or outward rectifier	I _A inactivatable I _or component	BK-like current fluctuations	I _Na	I _{K ir} inward rectifier
Senescent AFSC (n = 18)
Number of cells	18	15	12	9	1
% of cells	100	83.33	66.67	50.00	5.56
Mean current density (pA/pF)	6.9	3.1	1.7	−2.8	−5.8
SD	8.0	2.7	1.5	3.0	−
Cryopreserved AFSC (n = 19)
Number of cells	19	9	13	12	6
% of cells	100	47.37	68.42	63.16	31.58
Mean current density (pA/pF)	9.2	5.9	2.9	−13.1	−16.6
SD	9.1	8.5	2.4	23.7	24.9

Current densities were measured at +60 mV for I _or, I _A, and BK, at maximal peak amplitude (-10 or 0 mV) for I _Na, and at −120 mV for I _Kir
I _or outward rectifier current, I _A inactivatable (A-type) I _or current, I _Na voltage-dependent Na⁺ current, I _Kir inward rectifier K⁺ current

ISSN: 1880-6562