Fig. 2

Changes in total (a), myofibrillar (b), and soluble protein contents (c) of soleus muscle after bupivacaine injection with or without application of icing or heat stress. Values are means ± SEM. n = 6–8/group at each time point. See Fig. 1 for the abbreviations. ^#,§Significant main effect of treatment and time revealed by two-way ANOVA, respectively (p < 0.05). ^¶Significant interaction between treatment and time revealed by two-way ANOVA (p < 0.05). *Significantly different from Con group in the same time point (p < 0.05). ^b,cSignificantly different from day 7 and day 15 in each group, respectively (p < 0.05)