Fig. 6From: Immobilization induces nuclear accumulation of HDAC4 in rat skeletal muscleHDAC4-mediated regulation of disuse muscle atrophy-related gene expression. a Normal physiological conditions. b Denervation-induced catabolic conditions. c Immobilization-induced catabolic conditions. Disuse induced the nuclear accumulation of HDAC4, upregulation of Myogenin and MyoD, and subsequent E3 ligase expression. Bold arrows represent increased or decreased expressionBack to article page