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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain

Fig. 2

Effect of EDHB supplementation on vascular leakage. a Edema index (wet/dry wt ratio). Animals were exposed to 9144 m hypoxia, excised brain was kept for drying at 55 °C for 72 h and weighed before and after drying. b Vascular permeability was determined by sodium fluorescein dye leakage. Results are expressed in relative fluorescence units (RFU). C control, H hypoxia, D drug, DH drug hypoxia. Values are mean ± SD (n = 8/group). (C vs. H a p < 0.01; H vs. DH, c p < 0.05, b p < 0.01)

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