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Fig. 6 | The Journal of Physiological Sciences

Fig. 6

From: Somato-axodendritic release of oxytocin into the brain due to calcium amplification is essential for social memory

Fig. 6

Effects of cyclic ADP-ribose, ADP-ribose, and β-NAD+ on heat-induced calcium concentration rise. Time course of [Ca2+] i changes in Oregon Green-induced anterior hypothalamic neurons. At about 25 s after the beginning of each trace, cells were heated from 35 to 37 °C together with 100 μM cADPR, ADPR, β-NAD+ or without nucleotides (heat alone). Symbols indicate changes in [Ca2+] i levels, represented by the fluorescence intensity at each time point relative to resting intensity at time zero. N = 3−5 experiments. Mean ± SEM. Modified from [69]

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